Important: Therapy
- Samples should be taken prior to starting treatment.
- Send blood for culture if pyrexial.
- Send MSSU (carefully collected to avoid contamination.)
Uncomplicated Lower UTI
Micro Organisms
Enterobacteriaceae spp.
Escherichia coli
Staphylococcus saprophyticus
Duration
Females: 3 days
Males: 7 days
Important: Therapy
Trimethoprim oral 200mg 12 hourly
Important: Therapy
Nitrofurantoin oral modified release 100mg 12 hourly OR immediate release 50mg 6 hourly
Important: Notes
- Consider specialist referral for recurrent infection.
- Results of laboratory cultures and sensitivities usually available after overnight incubation.
- If culture results indicate sensitivity to ‘tetracycline’ then oxytetracycline (less expensive in primary care) or tetracycline should be considered. Doxycycline is inappropriate due to low renal excretion.
- In patients with CKD3 or above and/or those at risk of hyperkalaemia these agents may be unsuitable. Please check current prescribing advice as per BNF and seek specialist advice if alternative agent required.