Important:
Therapy
Vancomycin IV as per guideline
Use preferred calculator on Hospital portals page [intranet access only] or calculator on app for intermittent dosing
+
IV Gentamicin as per synergistic dosing guideline [intranet only]
+
Oral / IV Rifampicin 300-600mg 12 hourly
Notes:
Rifampicin helps eradicate bacteria attached to prosthetics.
Check gentamicin levels regularly, modify according to renal function.
Pre-dose (trough ) <1mg/L and peak (1 hour post-dose) 3-5mg/L
Check vancomycin levels regularly:
Pre-dose (trough) level of 15-20mg/L